The Museum of Byzantine Culture in Thessaloniki is an exemplary centre for the preservation, research and study of the Byzantine culture of Macedonia and more specifically of Thessaloniki, the second significant city of the Byzantine Empire. It is the first museum in Greece to be awarded in 2005 the Prize of the Council of Europe.

2,900 artefacts, organised in display units which narrate, in chronological order, "short stories" that present, in a comprehensive and pleasant way, aspects of byzantine art and culture, from its origins in late antiquity (3rd - 4th c. A. D.) to the Fall of Constantinople (1453), as well as surviving aspects of the former culture to the ages after the Fall to the 19th century.

The Museum is situated in an area just off the city centre, where one can find some of Thessaloniki’s most important cultural institutions as well as HELEXPO, the International Trade Fair of the city.