The Garki District is the area in the southwest corner of the city, having the Central District to the north and the Asokoro District to the east. The District is subdivided into units called "Areas". Garki uses a distinctive naming convention of "Area" to refer to parts of Garki. These are designated as Areas 1 to 11. Garki II is used to differentiate the area from Garki Area 2.

Garki is presently the principal business district of Abuja. Numerous buildings of interest are located in this area. Some of them include the General Post Office, Abuja International Conference Centre located on Herbert Macaulay Way, Nicon Luxury Hotel (formally known as Abuja Sofitel Hotel and Le Meridian), Agura Hotel and the Old Federal Secretariat Complex Buildings (Area 1). A new hotel, Hawthorn Suites Abuja is also located in Garki II. Area 2 is mainly used for residential purposes, although a zoological garden as well as the Garki Shopping Centre are located in Area 2. Banks and other commercial offices are located on Moshood Abiola Way in Area 7.

The Army Headquarters, Air force Headquarters and Navy Headquarters are all located in the Garki District. The tallest building in this district is the Radio House. This houses the Federal Ministry of Information and Communications, and the Federal Radio Corporation of Nigeria (FRCN).

RadioHouse The Nigerian Television Authority (NTA) Stations and Corporate Headquarters are also based in Garki. The Federal Capital Development Authority (FCDA) which oversees and runs the Administration of the Federal Capital Territory is located in Garki. The Office of the Minister of the Federal Capital Territory, Abuja is located in Area 10.

Other places of note include the Central Bank of Nigeria, Arts and Culture Centre and The Nigerian Police Mobile Force Headquarters in Area 10. The Abuja Municipal Area Council, which is the local Government administration, has its headquarters in Area 10. The new United States Embassy is also located in the Garki district.